Nurse Sean Doran returns from Africa and assumes the parental burden of caring for his aunt and nephew, a responsibility for which he is ill equipped. Soon, he reconnects with Becky, his childhood friend, but their budding romance is threatened by Sean's pathological reluctance to put down roots, and he has to finally decide what's most important to him.

Patrol officer Joe O'Brien is third-generation Irish in Charlestown. A tough cop with a soft interior, a loving wife and four adult children, Joe is diagnosed with Huntington's disease. As Joe's symptoms worsen and he's eventually stripped of his badge and more, Joe struggles to maintain hope and a sense of purpose, while his daughter Katie and her siblings must find the courage to either live a life "at risk" or learn their fate. "From award-winning,...

Eighteen-year-old Eli discovers a shocking secret about his life and his family while working for a Nobel Prize-winning scientist whose specialty is genetic engineering.

"When Alec asks Jess out, she knows it won't work. Is Alec charming? Of course. Attractive? Definitely. Can she not stop thinking about him...yes, but that's also the problem. Because Jess has rules. And the first? Don't fall in love. What no one knows is that Jess has inherited Huntington's disease from the mother that she cares for. And while witnessing her own future play out, Jess has learnt to keep everyone and everything at arm's length. But...

"Seventeen-year-old Rose Levenson must decide whether or not she wants to take the test to find out if she has Huntington's disease, the degenerative disease that is slowly killing her mother"--